Utah Cancer Control Program A Unified Cancer Prevention Approach

What is Lynch Syndrome?

Lynch Syndrome is a hereditary disorder caused by a mutation in a repair gene. Individuals affected with this syndrome have a higher than normal chance of developing colorectal cancer, and a specific type of uterine cancer called endometrial cancer, and various other types of aggressive cancers.

The only known method of accurately diagnosing Lynch syndrome is through genetic testing.


Who is at risk?

One set of criteria used to identify Lynch syndrome is listed below:

  • Developing colorectal cancer younger than age 50.
  • Developing colorectal cancer and other cancers linked with Lynch syndrome separately or at the same time.
  • Developing colorectal cancer with tumor features linked to Lynch syndrome at an age younger than 60.
  • Colorectal cancer in one or more first-degree relatives who also has or has had another Lynch syndrome-related cancer, with one of these cancers developing before age 50.
  • Colorectal cancer in two or more first- or second-degree relatives with another Lynch syndrome-related cancer. (1)


Lynch Syndrome Resources

CDC-Lynch Syndrome

I have Lynch Syndrome

Lynch Syndrome International



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1) Cancer.net